Efficacy and safety of Interferon-alpha (PDferon B®) and Ribavirin Combination Therapy in patients with Chronic Hepatitis C in Iran
نویسنده
چکیده
Seyed-Moayed Alavian MD 1, Masoud Ahmadzad Asl MD 2, Maryam Keshvari MD 3, Bita Behnava MD 4, Bashir Hajibeigi MD 5 1 Associate Professor of Gastroenterology; Department of Gastroenterology, Baqiyatallah University of Medical Sciences; Dean of Tehran Hepatitis Center, Tehran, Iran 2 Methodology and Statistics Consultant; Nikan Health Researchers Institute, Tehran Hepatitis Center, Tehran, Iran 3 Infectious Specialist; Blood Transfusion Research Center, Iran Blood Transfusion Organization, Tehran, Iran 4 Infectious Specialist; Tehran Hepatitis Center, Tehran, Iran 5 Blood Transfusion Research Center, Iran Blood Transfusion Organization, Tehran, Iran Efficacy and safety of Interferon-alpha (PDferon B®) and Ribavirin Combination Therapy in patients with Chronic Hepatitis C in Iran
منابع مشابه
EFFICACY AND SAFETY OF COMBINATION THERAPY OF INTERFERON-ALPHA 2B PLUS RIBAVIRIN FOR CHRONIC HEPATITIS C
Introduction: The aim of this study is to assess the therapeutic efficacy and safety of a particular brand of IFN alpha (PDferon B®) in combination with ribavirin (RlBA) on Iranian patients with chronic hepatitis C (CHC). The addition of RIBA to the standard treatment with interferon (IFN) alpha led to an improvement in sustained virologic response (SVR) from less than 20% with IFN monother...
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ABSTRACT Background: Combination therapy with interferon and ribavirin is the most effective treatment for chronic hepatitis C today. The aim of this study was to evaluate the efficacy and safety of thrice-weekly Heberon (interferon alfa-2b) in combination with ribavirin as first -line treatment of chronic hepatitis C. Methods: A total of97 treatment-naive patients received Heberon three milli...
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Introduction: The aim of this study is to assess the therapeutic efficacy and safety of a particular brand ofiFN alpha (PDferon B®) in combination with ribavirin (RlBA) on Iranian patients with chronic hepatitis C (CHC). The addition ofRIBA to the standard treatment with interferon (IFN) alpha led to an improvement in sustained virologic response (SVR) from less than 20% with IFN monotherapy to...
متن کاملمقایسه پاسخ درمانی مداوم بیماران مبتلا به هپاتیت مزمن C با رژیم اینترفرون معمولی در مقابل پگیلیتد اینترفرون
Introduction: Based on data from recent trials, peginterferon and ribavirin combination therapy is the standard of care in treating patients with chronic HCV infection, but because of high costs, many patients may deprive from treatment. Methods: We conducted a clinical trial on HCV patients in Yazd in gastroenterology clinic. Thirty patients received conventional subcutaneous interferon alf...
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Up to 30% of Iranian adult multi-transfused thalassemic patients are infected with hepatitis C virus (HCV) which can intensify the progression of liver disease caused by iron overload in this group of patients. Our aim was to assess the biochemical and virological response of interferon alfa (INF-α) and its safety in thalassemic patients with chronic HCV infection. This trial was a single c...
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